Diabetes

Diabetes and Astaxanthin

 Diabetes mellitus is a worldwide epidemic that is critically linked to the prevalence of obesity. More than 220 million suffer from diabetes, and by the year 2030 the figures are expected to grow to 360 million. Diabetic complications may lead to heart disease (approximately 65% of death amongst the diabetic patients), blindness, kidney failure and amputations. Even though we cannot evade type I diabetes which is influenced by heredity, fortunately type II diabetes is preventable by, for example, making dietary changes, taking nutritional supplements and exercising. Type II diabetes is a problem that causes blood glucose level to rise higher than normal, and the body cannot use insulin properly. This is called ‘’insulin resistance’’ which is induced by the increment of intracellular oxidative stress generated by TNF-α (inflammatory cytokine) or palmitate. The study indicated that astaxanthin ameliorates insulin resistance by restoring insulin-induced Akt phosphorylation attenuated by TNF-α or palmitate. Furthermore, astaxanthin likewise supports insulin activity by promoting the membrane translocation of GLUT4 in order to reduce blood glucose, and suppressing the phosphorylation of stress kinases to inhibit the negative feedback of the insulin signal. A large body of scientific research as well as testimonial evidence suggests that astaxanthin can commit to prevent prediabetes and improve diabetes health. For more details on how natural astaxanthin can support and maintain good diabetes health, please contact us for an expanded version of this digest.